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1

Finding the end: recruitment of telomerase to telomeres

Nandakumar, Jayakrishnan, Cech, Thomas R.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2013

Language:

english

File:

PDF, 892 KB

english, 2013

2

Restructuring α-pinene: novel entry into diverse polycarbocyclic frameworks

Goverdhan Mehta, Jayakrishnan Nandakumar

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 77 KB

english, 2001

3

Novel tandem ring-opening/ring-closing metathesis reactions of functionalized cyclohexenoids derived from (−)-α-pinene

Goverdhan Mehta, Jayakrishnan Nandakumar

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 76 KB

english, 2002

4

Structural basis for nick recognition by a minimal pluripotent DNA ligase

Nair, Pravin A, Nandakumar, Jayakrishnan, Smith, Paul, Odell, Mark, Lima, Christopher D, Shuman, Stewart

Journal:

Nature Structural and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 942 KB

english, 2007

5

RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward

Jayakrishnan Nandakumar, Stewart Shuman, Christopher D. Lima

Journal:

Year:

2006

Language:

english

File:

PDF, 817 KB

english, 2006

6

How an RNA Ligase Discriminates RNA versus DNA Damage

Jayakrishnan Nandakumar, Stewart Shuman

Journal:

Year:

2004

Language:

english

File:

PDF, 452 KB

english, 2004

7

Last Stop on the Road to Repair: Structure of E. coli DNA Ligase Bound to Nicked DNA-Adenylate

Jayakrishnan Nandakumar, Pravin A. Nair, Stewart Shuman

Journal:

Year:

2007

Language:

english

File:

PDF, 3.19 MB

english, 2007

8

RNA Repair: An Antidote to Cytotoxic Eukaryal RNA Damage

Jayakrishnan Nandakumar, Beate Schwer, Raffael Schaffrath, Stewart Shuman

Journal:

Year:

2008

Language:

english

File:

PDF, 894 KB

english, 2008

9

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity

Nandakumar, Jayakrishnan, Bell, Caitlin F., Weidenfeld, Ina, Zaug, Arthur J., Leinwand, Leslie A., Cech, Thomas R.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.37 MB

english, 2012

10

Dual Mechanisms whereby a Broken RNA End Assists the Catalysis of Its Repair by T4 RNA Ligase 2

Nandakumar, Jayakrishnan, Shuman, Stewart

Journal:

Journal of Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 664 KB

english, 2005

11

How Telomeric Protein POT1 Avoids RNA to Achieve Specificity for Single-Stranded DNA

Jayakrishnan Nandakumar, Elaine R. Podell, Thomas R. Cech and Titia de Lange

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.54 MB

english, 2010

12

Structural and functional consequences of a disease mutation in the telomere protein TPP1

Bisht, Kamlesh, Smith, Eric M., Tesmer, Valerie M., Nandakumar, Jayakrishnan

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.43 MB

english, 2016

13

A lentivirus-free inducible CRISPR-Cas9 system for efficient targeting of human genes

Bisht, Kamlesh, Grill, Sherilyn, Graniel, Jacqueline, Nandakumar, Jayakrishnan

Journal:

Analytical Biochemistry

Year:

2017

Language:

english

File:

PDF, 1.48 MB

english, 2017

14

Dissecting the telomere–inner nuclear membrane interface formed in meiosis

Pendlebury, Devon F, Fujiwara, Yasuhiro, Tesmer, Valerie M, Smith, Eric M, Shibuya, Hiroki, Watanabe, Yoshinori, Nandakumar, Jayakrishnan

Journal:

Nature Structural and Molecular Biology

Year:

2017

Language:

english

File:

PDF, 3.28 MB

english, 2017

15

The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action

Grill, Sherilyn, Tesmer, Valerie M., Nandakumar, Jayakrishnan

Journal:

Year:

2018

Language:

english

File:

PDF, 3.00 MB

english, 2018

16

CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length

Gu, Peili, Jia, Shuting, Takasugi, Taylor, Smith, Eric, Nandakumar, Jayakrishnan, Hendrickson, Eric, Chang, Sandy

Journal:

Year:

2018

Language:

english

File:

PDF, 3.13 MB

english, 2018

17

Structural biology of telomeres and telomerase

Smith, Eric M., Pendlebury, Devon F., Nandakumar, Jayakrishnan

Journal:

Cellular and Molecular Life Sciences

Year:

2019

Language:

english

File:

PDF, 4.03 MB

english, 2019

18

Combining conservation and species-specific differences to determine how human telomerase binds telomeres

Tesmer, Valerie M., Smith, Eric M., Danciu, Oana, Padmanaban, Shilpa, Nandakumar, Jayakrishnan

Journal:

Proceedings of the National Academy of Sciences

Year:

2019

File:

PDF, 2.27 MB

2019

19

Small Molecules Restore Telomeres in Patient Stem Cells

Brenner, Kirsten Ann, Nandakumar, Jayakrishnan

Journal:

Trends in Pharmacological Sciences

Year:

2020

File:

PDF, 419 KB

2020

20

Molecular mechanisms of telomere biology disorders

Grill, Sherilyn, Nandakumar, Jayakrishnan

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 426 KB

2020